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A hidden Markov model for haplotype inference for present-absent data of clustered genes using identified haplotypes and haplotype patterns

The majority of killer cell immunoglobin-like receptor (KIR) genes are detected as either present or absent using locus-specific genotyping technology. Ambiguity arises from the presence of a specific KIR gene since the exact copy number (one or two) of that gene is unknown. Therefore, haplotype inf...

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Detalles Bibliográficos
Autores principales: Wu, Jihua, Chen, Guo-Bo, Zhi, Degui, Liu, Nianjun, Zhang, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129397/
https://www.ncbi.nlm.nih.gov/pubmed/25161663
http://dx.doi.org/10.3389/fgene.2014.00267