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Fixed-target protein serial microcrystallography with an x-ray free electron laser

We present results from experiments at the Linac Coherent Light Source (LCLS) demonstrating that serial femtosecond crystallography (SFX) can be performed to high resolution (~2.5 Å) using protein microcrystals deposited on an ultra-thin silicon nitride membrane and embedded in a preservation medium...

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Detalles Bibliográficos
Autores principales: Hunter, Mark S., Segelke, Brent, Messerschmidt, Marc, Williams, Garth J., Zatsepin, Nadia A., Barty, Anton, Benner, W. Henry, Carlson, David B., Coleman, Matthew, Graf, Alexander, Hau-Riege, Stefan P., Pardini, Tommaso, Seibert, M. Marvin, Evans, James, Boutet, Sébastien, Frank, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129423/
https://www.ncbi.nlm.nih.gov/pubmed/25113598
http://dx.doi.org/10.1038/srep06026