TENSION ON THE LINKER GATES THE ATP-DEPENDENT RELEASE OF DYNEIN FROM MICROTUBULES

Cytoplasmic dynein is a dimeric motor that transports intracellular cargoes towards the minus-end of microtubules (MTs). In contrast to other processive motors, stepping of the dynein motor domains (heads) is not precisely coordinated. Therefore, the mechanism of dynein processivity remains unclear....

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Detalles Bibliográficos
Autores principales: Cleary, Frank B., Dewitt, Mark A., Bilyard, Thomas, Htet, Zaw Min, Belyy, Vladislav, Chan, Danna D., Chang, Amy Y., Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129465/
https://www.ncbi.nlm.nih.gov/pubmed/25109325
http://dx.doi.org/10.1038/ncomms5587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129465/
https://www.ncbi.nlm.nih.gov/pubmed/25109325
http://dx.doi.org/10.1038/ncomms5587

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