δ-Tocotrienol Oxazine Derivative Antagonizes Mammary Tumor Cell Compensatory Response to CoCl(2)-Induced Hypoxia

In response to low oxygen supply, cancer cells elevate production of HIF-1α, a hypoxia-inducible transcription factor that subsequently acts to stimulate blood vessel formation and promote survival. Studies were conducted to determine the role of δ-tocotrienol and a semisynthetic δ-tocotrienol oxazi...

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Detalles Bibliográficos
Autores principales: Ananthula, Suryatheja, Parajuli, Parash, Behery, Fathy A., Alayoubi, Alaadin Y., Nazzal, Sami, El Sayed, Khalid, Sylvester, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129965/
https://www.ncbi.nlm.nih.gov/pubmed/25140303
http://dx.doi.org/10.1155/2014/285752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129965/
https://www.ncbi.nlm.nih.gov/pubmed/25140303
http://dx.doi.org/10.1155/2014/285752

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