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Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas' Heart Disease

Background. Chagas disease (CD) is characterized by parasite persistence and immunological unbalance favoring systemic inflammatory profile. Chronic chagasic cardiomyopathy, the main manifestation of CD, occurs in a TNF-enriched milieu and frequently progresses to heart failure. Aim of the Study. To...

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Detalles Bibliográficos
Autores principales: Pereira, Isabela Resende, Vilar-Pereira, Glaucia, Silva, Andrea Alice, Moreira, Otacilio Cruz, Britto, Constança, Sarmento, Ellen Diana Marinho, Lannes-Vieira, Joseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130030/
https://www.ncbi.nlm.nih.gov/pubmed/25140115
http://dx.doi.org/10.1155/2014/798078