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Live attenuated hepatitis A vaccines developed in China
Two live, attenuated hepatitis A vaccines, H(2) and LA-1 virus strains, were developed through serial passages of the viruses in cell cultures at 32 °C and 35 °C respectively. Both vaccines were safe and immunogenic, providing protection against clinical hepatitis A in 95% of the vaccinees, with a s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130259/ https://www.ncbi.nlm.nih.gov/pubmed/24280971 http://dx.doi.org/10.4161/hv.27124 |