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Live attenuated hepatitis A vaccines developed in China

Two live, attenuated hepatitis A vaccines, H(2) and LA-1 virus strains, were developed through serial passages of the viruses in cell cultures at 32 °C and 35 °C respectively. Both vaccines were safe and immunogenic, providing protection against clinical hepatitis A in 95% of the vaccinees, with a s...

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Detalles Bibliográficos
Autores principales: Xu, Zhi-Yi, Wang, Xuan-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130259/
https://www.ncbi.nlm.nih.gov/pubmed/24280971
http://dx.doi.org/10.4161/hv.27124