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Protection Versus Pathology in Aviremic and High Viral Load HIV-2 Infection—The Pivotal Role of Immune Activation and T-cell Kinetics

Background. Many human immunodeficiency virus (HIV)–2-infected individuals remain aviremic and behave as long-term non-progressors but some progress to AIDS. We hypothesized that immune activation and T-cell turnover would be critical determinants of non-progressor/progressor status. Methods. We stu...

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Detalles Bibliográficos
Autores principales: Hegedus, Andrea, Nyamweya, Samuel, Zhang, Yan, Govind, Sheila, Aspinall, Richard, Mashanova, Alla, Jansen, Vincent A. A., Whittle, Hilton, Jaye, Assan, Flanagan, Katie L., Macallan, Derek C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130319/
https://www.ncbi.nlm.nih.gov/pubmed/24803534
http://dx.doi.org/10.1093/infdis/jiu165