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Accelerated Chromatin Biochemistry Using DNA-Barcoded Nucleosome Libraries

Elucidating the molecular details of how chromatin-associated factors deposit, remove and recognize histone posttranslational modification (‘PTM’) signatures remains a daunting task in the epigenetics field. Here, we introduce a versatile platform that greatly accelerates biochemical investigations...

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Detalles Bibliográficos
Autores principales: Nguyen, Uyen T. T., Bittova, Lenka, Müller, Manuel M., Fierz, Beat, David, Yael, Houck-Loomis, Brian, Feng, Vanessa, Dann, Geoffrey P., Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130351/
https://www.ncbi.nlm.nih.gov/pubmed/24997861
http://dx.doi.org/10.1038/nmeth.3022