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Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

BACKGROUND: HIV-1 entry into host cells is mediated by interactions between the virus envelope glycoprotein (gp120/gp41) and host-cell receptors. N-glycans represent approximately 50% of the molecular mass of gp120 and serve as potential antigenic determinants and/or as a shield against immune recog...

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Detalles Bibliográficos
Autores principales: Raska, Milan, Czernekova, Lydie, Moldoveanu, Zina, Zachova, Katerina, Elliott, Matt C, Novak, Zdenek, Hall, Stacy, Hoelscher, Michael, Maboko, Leonard, Brown, Rhubell, Smith, Phillip D, Mestecky, Jiri, Novak, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130436/
https://www.ncbi.nlm.nih.gov/pubmed/25120578
http://dx.doi.org/10.1186/1742-6405-11-23