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Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection
BACKGROUND: HIV-1 entry into host cells is mediated by interactions between the virus envelope glycoprotein (gp120/gp41) and host-cell receptors. N-glycans represent approximately 50% of the molecular mass of gp120 and serve as potential antigenic determinants and/or as a shield against immune recog...
Autores principales: | Raska, Milan, Czernekova, Lydie, Moldoveanu, Zina, Zachova, Katerina, Elliott, Matt C, Novak, Zdenek, Hall, Stacy, Hoelscher, Michael, Maboko, Leonard, Brown, Rhubell, Smith, Phillip D, Mestecky, Jiri, Novak, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130436/ https://www.ncbi.nlm.nih.gov/pubmed/25120578 http://dx.doi.org/10.1186/1742-6405-11-23 |
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