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Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling

BACKGROUND: Peptidyl-prolyl isomerase cyclophilin A (CypA) plays important roles in signaling, protein translocation, inflammation, and cancer formation. However, little is known about the mechanisms by which CypA exerts its effects. C57BL/6 Ppia (encoding CypA)-deficient embryonic fibroblasts show...

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Detalles Bibliográficos
Autores principales: Sun, Shan, Guo, Mian, Zhang, James Beiji, Ha, Albert, Yokoyama, Kazunari K., Chiu, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130471/
https://www.ncbi.nlm.nih.gov/pubmed/25119989
http://dx.doi.org/10.1371/journal.pone.0096211