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Fgfr1 Inactivation in the Mouse Telencephalon Results in Impaired Maturation of Interneurons Expressing Parvalbumin

Fibroblast growth factors (Fgfs) and their receptors (Fgfr) are expressed in the developing and adult CNS. Previous studies demonstrated a decrease in cortical interneurons and locomotor hyperactivity in mice with a conditional Fgfr1 deletion generated in radial glial cells during midneurogenesis (F...

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Detalles Bibliográficos
Autores principales: Smith, Karen Müller, Maragnoli, Maria Elisabetta, Phull, Pooja M., Tran, Kathy May, Choubey, Lisha, Vaccarino, Flora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130531/
https://www.ncbi.nlm.nih.gov/pubmed/25116473
http://dx.doi.org/10.1371/journal.pone.0103696