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TORC1 Regulates Pah1 Phosphatidate Phosphatase Activity via the Nem1/Spo7 Protein Phosphatase Complex

The evolutionarily conserved target of rapamycin complex 1 (TORC1) controls growth-related processes such as protein, nucleotide, and lipid metabolism in response to growth hormones, energy/ATP levels, and amino acids. Its deregulation is associated with cancer, type 2 diabetes, and obesity. Among o...

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Detalles Bibliográficos
Autores principales: Dubots, Emmanuelle, Cottier, Stéphanie, Péli-Gulli, Marie-Pierre, Jaquenoud, Malika, Bontron, Séverine, Schneiter, Roger, De Virgilio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130541/
https://www.ncbi.nlm.nih.gov/pubmed/25117580
http://dx.doi.org/10.1371/journal.pone.0104194