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TORC1 Regulates Pah1 Phosphatidate Phosphatase Activity via the Nem1/Spo7 Protein Phosphatase Complex
The evolutionarily conserved target of rapamycin complex 1 (TORC1) controls growth-related processes such as protein, nucleotide, and lipid metabolism in response to growth hormones, energy/ATP levels, and amino acids. Its deregulation is associated with cancer, type 2 diabetes, and obesity. Among o...
Autores principales: | Dubots, Emmanuelle, Cottier, Stéphanie, Péli-Gulli, Marie-Pierre, Jaquenoud, Malika, Bontron, Séverine, Schneiter, Roger, De Virgilio, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130541/ https://www.ncbi.nlm.nih.gov/pubmed/25117580 http://dx.doi.org/10.1371/journal.pone.0104194 |
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