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The Major Cow Milk Allergen Bos d 5 Manipulates T-Helper Cells Depending on Its Load with Siderophore-Bound Iron

The mechanisms of allergic sensitization to milk are still elusive. The major allergen Bos d 5 belongs to the lipocalin-family and thus is able to transport numerous ligands. In this study we investigated its ability to bind to iron-siderophore complexes and tested the immune-modulatory properties o...

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Detalles Bibliográficos
Autores principales: Roth-Walter, Franziska, Pacios, Luis F., Gomez-Casado, Cristina, Hofstetter, Gerlinde, Roth, Georg A., Singer, Josef, Diaz-Perales, Araceli, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130594/
https://www.ncbi.nlm.nih.gov/pubmed/25117976
http://dx.doi.org/10.1371/journal.pone.0104803