Cargando…
The Major Cow Milk Allergen Bos d 5 Manipulates T-Helper Cells Depending on Its Load with Siderophore-Bound Iron
The mechanisms of allergic sensitization to milk are still elusive. The major allergen Bos d 5 belongs to the lipocalin-family and thus is able to transport numerous ligands. In this study we investigated its ability to bind to iron-siderophore complexes and tested the immune-modulatory properties o...
Autores principales: | Roth-Walter, Franziska, Pacios, Luis F., Gomez-Casado, Cristina, Hofstetter, Gerlinde, Roth, Georg A., Singer, Josef, Diaz-Perales, Araceli, Jensen-Jarolim, Erika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130594/ https://www.ncbi.nlm.nih.gov/pubmed/25117976 http://dx.doi.org/10.1371/journal.pone.0104803 |
Ejemplares similares
-
Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes
por: Roth-Walter, Franziska, et al.
Publicado: (2014) -
Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope
por: Hufnagl, Karin, et al.
Publicado: (2018) -
Iron-Deficiency in Atopic Diseases: Innate Immune Priming by Allergens and Siderophores
por: Roth-Walter, Franziska
Publicado: (2022) -
Retinoic acid‐loading of the major birch pollen allergen Bet v 1 may improve specific allergen immunotherapy: In silico, in vitro and in vivo data in BALB/c mice
por: Hufnagl, Karin, et al.
Publicado: (2020) -
Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity
por: Regner, Andreas, et al.
Publicado: (2022)