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Placental FKBP5 Genetic and Epigenetic Variation Is Associated with Infant Neurobehavioral Outcomes in the RICHS Cohort

Adverse maternal environments can lead to increased fetal exposure to maternal cortisol, which can cause infant neurobehavioral deficits. The placenta regulates fetal cortisol exposure and response, and placental DNA methylation can influence this function. FK506 binding protein (FKBP5) is a negativ...

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Detalles Bibliográficos
Autores principales: Paquette, Alison G., Lester, Barry M., Koestler, Devin C., Lesseur, Corina, Armstrong, David A., Marsit, Carmen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130612/
https://www.ncbi.nlm.nih.gov/pubmed/25115650
http://dx.doi.org/10.1371/journal.pone.0104913