Hot Melt Extruded Amorphous Solid Dispersion of Posaconazole with Improved Bioavailability: Investigating Drug-Polymer Miscibility with Advanced Characterisation

Invasive antifungal infections are reasons for morbidity and mortality in immunogenic patients worldwide. Posaconazole is a most promising antifungal agent against all types of invasive infections with high % of cure rate. The marketed suspension formulation has low bioavailability and is needed to...

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Detalles Bibliográficos
Autores principales: Fule, Ritesh, Amin, Purnima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131112/
https://www.ncbi.nlm.nih.gov/pubmed/25143935
http://dx.doi.org/10.1155/2014/146781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131112/
https://www.ncbi.nlm.nih.gov/pubmed/25143935
http://dx.doi.org/10.1155/2014/146781

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