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MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB

Recently, we have shown that the treatment of cells with proteasome inhibitor MG-132 results in the induction of expression of monocyte chemotactic protein-1 induced protein 1 (MCPIP1). MCPIP1 is a ribonuclease, responsible for the degradation of transcripts encoding certain pro-inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Skalniak, Lukasz, Dziendziel, Monika, Jura, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131145/
https://www.ncbi.nlm.nih.gov/pubmed/24992982
http://dx.doi.org/10.1007/s11010-014-2134-z