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Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins

By virtue of their general ability to bind (hold) translocating or unfolding polypeptides otherwise doomed to aggregate, molecular chaperones are commonly dubbed “holdases”. Yet, chaperones also carry physiological functions that do not necessitate prevention of aggregation, such as altering the nat...

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Detalles Bibliográficos
Autores principales: Mattoo, Rayees U. H., Goloubinoff, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131146/
https://www.ncbi.nlm.nih.gov/pubmed/24760129
http://dx.doi.org/10.1007/s00018-014-1627-y