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Highly conserved salt bridge stabilizes a proteinase K subfamily enzyme, Aqualysin I, from Thermus aquaticus YT-1

The proteinase K subfamily enzymes, thermophilic Aqualysin I (AQN) from Thermus aquaticus YT-1 and psychrophilic serine protease (VPR) from Vibrio sp. PA-44, have six and seven salt bridges, respectively. To understand the possible significance of salt bridges in the thermal stability of AQN, we pre...

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Detalles Bibliográficos
Autores principales: Sakaguchi, Masayoshi, Osaku, Kanae, Maejima, Susumu, Ohno, Nao, Sugahara, Yasusato, Oyama, Fumitaka, Kawakita, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131155/
https://www.ncbi.nlm.nih.gov/pubmed/25136511
http://dx.doi.org/10.1186/s13568-014-0059-2