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Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks

BACKGROUND: Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context-specific and dynamic in nature. To systematically characterize the selective...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Zhang, Bai, Hoffman, Eric P, Clarke, Robert, Zhang, Zhen, Shih, Ie-Ming, Xuan, Jianhua, Herrington, David M, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131167/
https://www.ncbi.nlm.nih.gov/pubmed/25055984
http://dx.doi.org/10.1186/s12918-014-0087-1