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Knowledge-fused differential dependency network models for detecting significant rewiring in biological networks
BACKGROUND: Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context-specific and dynamic in nature. To systematically characterize the selective...
Autores principales: | Tian, Ye, Zhang, Bai, Hoffman, Eric P, Clarke, Robert, Zhang, Zhen, Shih, Ie-Ming, Xuan, Jianhua, Herrington, David M, Wang, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131167/ https://www.ncbi.nlm.nih.gov/pubmed/25055984 http://dx.doi.org/10.1186/s12918-014-0087-1 |
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