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Ubiquitination by SAG regulates macrophage survival/death and immune response during infection

The checkpoint between the life and death of macrophages is crucial for the host's frontline immune defense during acute phase infection. However, the mechanism as to how the immune cell equilibrates between apoptosis and immune response is unclear. Using in vitro and ex vivo approaches, we sho...

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Detalles Bibliográficos
Autores principales: Chang, S C, Ding, J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131172/
https://www.ncbi.nlm.nih.gov/pubmed/24786833
http://dx.doi.org/10.1038/cdd.2014.54