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Ubiquitination by SAG regulates macrophage survival/death and immune response during infection
The checkpoint between the life and death of macrophages is crucial for the host's frontline immune defense during acute phase infection. However, the mechanism as to how the immune cell equilibrates between apoptosis and immune response is unclear. Using in vitro and ex vivo approaches, we sho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131172/ https://www.ncbi.nlm.nih.gov/pubmed/24786833 http://dx.doi.org/10.1038/cdd.2014.54 |