Integrated high-throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis

The restoration of p53 tumor suppressor function is a promising therapeutic strategy to combat cancer. However, the biological outcomes of p53 activation, ranging from the promotion of growth arrest to the induction of cell death, are hard to predict, which limits the clinical application of p53-bas...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, H, Zhang, Y, Ströse, A, Tedesco, D, Gurova, K, Selivanova, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131181/
https://www.ncbi.nlm.nih.gov/pubmed/24971482
http://dx.doi.org/10.1038/cdd.2014.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131181/
https://www.ncbi.nlm.nih.gov/pubmed/24971482
http://dx.doi.org/10.1038/cdd.2014.69

Ejemplares similares