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Getting TRAIL back on track for cancer therapy

Unlike other members of the TNF superfamily, the TNF-related apoptosis-inducing ligand (TRAIL, also known as Apo2L) possesses the unique capacity to induce apoptosis selectively in cancer cells in vitro and in vivo. This exciting discovery provided the basis for the development of TRAIL-receptor ago...

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Detalles Bibliográficos
Autores principales: Lemke, J, von Karstedt, S, Zinngrebe, J, Walczak, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131183/
https://www.ncbi.nlm.nih.gov/pubmed/24948009
http://dx.doi.org/10.1038/cdd.2014.81