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The newt reprograms mature RPE cells into a unique multipotent state for retinal regeneration

The reprogramming of retinal pigment epithelium (RPE) cells in the adult newt immediately after retinal injury is an area of active research for the study of retinal disorders and regeneration. We demonstrate here that unlike embryonic/larval retinal regeneration, adult newt RPE cells are not direct...

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Detalles Bibliográficos
Autores principales: Islam, Md. Rafiqul, Nakamura, Kenta, Casco-Robles, Martin Miguel, Kunahong, Ailidana, Inami, Wataru, Toyama, Fubito, Maruo, Fumiaki, Chiba, Chikafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131214/
https://www.ncbi.nlm.nih.gov/pubmed/25116407
http://dx.doi.org/10.1038/srep06043