Single chromosome transcriptional profiling reveals chromosome-level regulation of gene expression

Here we report iceFISH, a multiplex imaging method for measuring gene expression and chromosome structure simultaneously on single chromosomes. We demonstrate that chromosomal translocations can alter transcription chromosome-wide, finding substantial differences in transcriptional frequency between...

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Detalles Bibliográficos
Autores principales: Levesque, Marshall J., Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131260/
https://www.ncbi.nlm.nih.gov/pubmed/23416756
http://dx.doi.org/10.1038/nmeth.2372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131260/
https://www.ncbi.nlm.nih.gov/pubmed/23416756
http://dx.doi.org/10.1038/nmeth.2372

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