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Allowing for non-adherence to treatment in a randomized controlled trial of two antidepressants (citalopram versus reboxetine): an example from the GENPOD trial

BACKGROUND: Meta-analyses suggest that reboxetine may be less effective than other antidepressants. Such comparisons may be biased by lower adherence to reboxetine and subsequent handling of missing outcome data. This study illustrates how to adjust for differential non-adherence and hence derive an...

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Detalles Bibliográficos
Autores principales: Wiles, N. J., Fischer, K., Cowen, P., Nutt, D., Peters, T. J., Lewis, G., White, I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131263/
https://www.ncbi.nlm.nih.gov/pubmed/25065692
http://dx.doi.org/10.1017/S0033291714000221