Gene Expression Profiling in Mouse Embryonic Stem Cells Reveals Glycogen Synthase Kinase-3-Dependent Targets of Phosphatidylinositol 3-Kinase and Wnt/β-Catenin Signaling Pathways

Glycogen synthase kinase-3 (Gsk-3) activity is an important regulator of numerous signal transduction pathways. Gsk-3 activity is the sum of two largely redundant proteins, Gsk-3α and Gsk-3β, and in general, Gsk-3 is a negative regulator of cellular signaling. Genetic deletion of both Gsk-3α and Gsk...

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Detalles Bibliográficos
Autores principales: Bartman, Colleen M., Egelston, Jennifer, Kattula, Sravya, Zeidner, Leigh C., D’Ippolito, Anthony, Doble, Bradley W., Phiel, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131280/
https://www.ncbi.nlm.nih.gov/pubmed/25165462
http://dx.doi.org/10.3389/fendo.2014.00133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131280/
https://www.ncbi.nlm.nih.gov/pubmed/25165462
http://dx.doi.org/10.3389/fendo.2014.00133

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