β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons

Despite advances in understanding the signaling mechanisms involved in the development and maintenance of chronic pain, the pharmacologic treatment of chronic pain has seen little advancement. Agonists at the mu opioid receptor (MOPr) continue to be vital in the treatment of many forms of chronic pa...

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Detalles Bibliográficos
Autores principales: Rowan, Matthew P, Szteyn, Kalina, Doyle, Allison P, Gomez, Ruben, Henry, Michael A, Jeske, Nathaniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131480/
https://www.ncbi.nlm.nih.gov/pubmed/25085415
http://dx.doi.org/10.1186/1744-8069-10-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131480/
https://www.ncbi.nlm.nih.gov/pubmed/25085415
http://dx.doi.org/10.1186/1744-8069-10-50

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