The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote

BACKGROUND: Inheritance of the F variant of alpha-1-antitrypsin is associated with normal circulating protein levels, but it is believed to be dysfunctional in its ability to inhibit neutrophil elastase and therefore has been implicated as a susceptibility factor for the development of emphysema. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinden, Nicola Jane, Koura, Firas, Stockley, Robert Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131482/
https://www.ncbi.nlm.nih.gov/pubmed/25098359
http://dx.doi.org/10.1186/1471-2466-14-132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131482/
https://www.ncbi.nlm.nih.gov/pubmed/25098359
http://dx.doi.org/10.1186/1471-2466-14-132

Ejemplares similares