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TGF-β mediated DNA methylation in prostate cancer

Almost all tumors harbor a defective negative feedback loop of signaling by transforming growth factor-β (TGF-β). Epigenetic mechanisms of gene regulation, including DNA methylation, are fundamental to normal cellular function and also play a major role in carcinogenesis. Recent evidence demonstrate...

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Detalles Bibliográficos
Autores principales: Lee, Chung, Zhang, Qiang, Zi, Xaolin, Dash, Atreya, Soares, Marcelo B, Rahmatpanah, Farahnaz, Jia, Zhenyu, McClelland, Michael, Mercola, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131550/
https://www.ncbi.nlm.nih.gov/pubmed/25133096
http://dx.doi.org/10.3978/j.issn.2223-4683.2012.05.06