Cargando…

TGF-β mediated DNA methylation in prostate cancer

Almost all tumors harbor a defective negative feedback loop of signaling by transforming growth factor-β (TGF-β). Epigenetic mechanisms of gene regulation, including DNA methylation, are fundamental to normal cellular function and also play a major role in carcinogenesis. Recent evidence demonstrate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Chung, Zhang, Qiang, Zi, Xaolin, Dash, Atreya, Soares, Marcelo B, Rahmatpanah, Farahnaz, Jia, Zhenyu, McClelland, Michael, Mercola, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131550/ https://www.ncbi.nlm.nih.gov/pubmed/25133096 http://dx.doi.org/10.3978/j.issn.2223-4683.2012.05.06

Ejemplares similares

Role of the Adjacent Stroma Cells in Prostate Cancer Development and Progression: Synergy between TGF-β and IGF Signaling
por: Lee, Chung, et al.
Publicado: (2014)

An Accurate Prostate Cancer Prognosticator Using a Seven-Gene Signature Plus Gleason Score and Taking Cell Type Heterogeneity into Account
por: Chen, Xin, et al.
Publicado: (2012)

The identification of trans-associations between prostate cancer GWAS SNPs and RNA expression differences in tumor-adjacent stroma
por: Chen, Xin, et al.
Publicado: (2015)

Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry
por: Kumar, Vinay, et al.
Publicado: (2021)

Expression Changes in the Stroma of Prostate Cancer Predict Subsequent Relapse
por: Jia, Zhenyu, et al.
Publicado: (2012)

Correction: Expression Changes in the Stroma of Prostate Cancer Predict Subsequent Relapse
por: Jia, Zhenyu, et al.
Publicado: (2012)

RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans
por: Rahmatpanah, Farah, et al.
Publicado: (2021)

Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk
por: Kumar, Vinay, et al.
Publicado: (2022)

A class of genes in the HER2 regulon that is poised for transcription in breast cancer cell lines and expressed in human breast tumors
por: Rahmatpanah, Farah B., et al.
Publicado: (2014)

Transcriptome Analysis of Ovarian and Uterine Clear Cell Malignancies
por: Alldredge, Jill, et al.
Publicado: (2020)

Algorithmic Discovery of Methylation “Hot Spots” in DNA from Lymphoma Patients
por: Papageorgio, Chris, et al.
Publicado: (2008)

Six stroma-based RNA markers diagnostic for prostate cancer in European-Americans validated at the RNA and protein levels in patients in China
por: Zhu, Jianguo, et al.
Publicado: (2015)

Early Growth Response 3 (Egr3) Is Highly Over-Expressed in Non-Relapsing Prostate Cancer but Not in Relapsing Prostate Cancer
por: Pio, Rebecca, et al.
Publicado: (2013)

Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors
por: Rahmatpanah, Farah, et al.
Publicado: (2018)

Correction: Airway epithelial cells prime plasmacytoid dendritic cells to respond to pathogens via secretion of growth factors
por: Rahmatpanah, Farah, et al.
Publicado: (2019)

DNA Methylation of TGFβ Target Genes: Epigenetic Control of TGFβ Functional Duality in Liver Cancer
por: Bévant, Kevin, et al.
Publicado: (2021)

Overexpression of Periostin in Stroma Positively Associated with Aggressive Prostate Cancer
por: Tian, Yuan, et al.
Publicado: (2015)

Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip
por: Arora, Shilpi, et al.
Publicado: (2008)

Correction: Overexpression of Periostin in Stroma Positively Associated with Aggressive Prostate Cancer
por: Tian, Yuan, et al.
Publicado: (2015)

TGF-β Regulates DNA Methyltransferase Expression in Prostate Cancer, Correlates with Aggressive Capabilities, and Predicts Disease Recurrence
por: Zhang, Qiang, et al.
Publicado: (2011)

miR-200a Prevents Renal Fibrogenesis Through Repression of TGF-β2 Expression
por: Wang, Bo, et al.
Publicado: (2011)

DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition
por: Zheng, Jianbo, et al.
Publicado: (2018)

Stromal TGF-β signaling induces AR activation in prostate cancer
por: Yang, Feng, et al.
Publicado: (2014)

Mechanisms navigating the TGF-β pathway in prostate cancer
por: Cao, Zheng, et al.
Publicado: (2015)

Disparities in the Utilization of Radiation Therapy for Prostate Cancer in the United States: A Comprehensive Review
por: Gardner, Ulysses, et al.
Publicado: (2022)

Inhibitors of DNA methylation support TGF-β1-induced IL11 expression in gingival fibroblasts
por: Sufaru, Irina-Georgeta, et al.
Publicado: (2017)

Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials
por: Jia, Zhenyu, et al.
Publicado: (2014)

Mysteries of TGF-β Paradox in Benign and Malignant Cells
por: Zhang, Qiang, et al.
Publicado: (2014)

Editorial: Therapeutic Opportunities and Innovative Biomarkers in Tumor Microenvironment
por: Xu, Kexin, et al.
Publicado: (2021)

Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells.
por: Brezden, C. B., et al.
Publicado: (1997)

TGFβ signaling limits lineage plasticity in prostate cancer
por: Hao, Yi, et al.
Publicado: (2018)

Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation
por: Freudenberg, Kristin, et al.
Publicado: (2018)

Absence of integrin-mediated TGFβ1 activation in vivo recapitulates the phenotype of TGFβ1-null mice
por: Yang, Zhiwei, et al.
Publicado: (2007)

Misrepair in Context: TGFβ Regulation of DNA Repair
por: Liu, Qi, et al.
Publicado: (2019)

LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia
por: He, Yao, et al.
Publicado: (2016)

Dynamic patterns of DNA methylation in the normal prostate epithelial differentiation program are targets of aberrant methylation in prostate cancer
por: Long, Mark D., et al.
Publicado: (2021)

Prostate Cancer Induced by Loss of Apc Is Restrained by TGFβ Signaling
por: Bjerke, Glen A., et al.
Publicado: (2014)

Opposing roles of TGFβ and BMP signaling in prostate cancer development
por: Lu, Xin, et al.
Publicado: (2017)

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis
por: Tian, Han, et al.
Publicado: (2023)

A Gradient Boosting Algorithm for Survival Analysis via Direct Optimization of Concordance Index
por: Chen, Yifei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_os86bt5r71smqspbmeale8c71b