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A reporter gene system for screening inhibitors of Wnt signaling pathway

Abnormal activation of canonical Wnt signaling has been associated with various types of cancer. Inhibitory reagents targeting the Wnt signaling have great potential to inhibit the growth of relevant tumors. Here we generated a cell-based screening strategy for identification of antagonists of the W...

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Detalles Bibliográficos
Autores principales: Li, Xing-Yao, Wang, Yuan-Yuan, Yuan, Chun-Mao, Hao, Xiao-Jiang, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131617/
http://dx.doi.org/10.1007/s13659-012-0094-0