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In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA

Drug-resistant tuberculosis (TB) threatens global TB control and is a major public health concern in several countries. We therefore developed a multiplex assay (LINE-TB/MDR) that is able to identify the most frequent mutations related to rifampicin (RMP) and isoniazid (INH) resistance. The assay is...

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Detalles Bibliográficos
Autores principales: Ferreira, Sergio Luiz Montego, Costa, Elis Regina Dalla, dos Santos, Paula Gonçalves, Gomes, Harrison Magdinier, Silva, Marcia Susana Nunes, Esteves, Leonardo Souza, Oliveira, Martha Maria, Maschmann, Raquel de Abreu, Kritski, Afrânio Lineu, Suffys, Philip Noel, Rossetti, Maria Lucia Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131782/
https://www.ncbi.nlm.nih.gov/pubmed/24821057
http://dx.doi.org/10.1590/0074-0276130469