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In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA
Drug-resistant tuberculosis (TB) threatens global TB control and is a major public health concern in several countries. We therefore developed a multiplex assay (LINE-TB/MDR) that is able to identify the most frequent mutations related to rifampicin (RMP) and isoniazid (INH) resistance. The assay is...
Autores principales: | Ferreira, Sergio Luiz Montego, Costa, Elis Regina Dalla, dos Santos, Paula Gonçalves, Gomes, Harrison Magdinier, Silva, Marcia Susana Nunes, Esteves, Leonardo Souza, Oliveira, Martha Maria, Maschmann, Raquel de Abreu, Kritski, Afrânio Lineu, Suffys, Philip Noel, Rossetti, Maria Lucia Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131782/ https://www.ncbi.nlm.nih.gov/pubmed/24821057 http://dx.doi.org/10.1590/0074-0276130469 |
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