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The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition

[Image: see text] Many pathogenic bacteria utilize the type III secretion system (T3SS) to translocate effector proteins directly into host cells, facilitating colonization. In enterohemmorhagic Escherichia coli (EHEC), a subset of T3SS effectors is essential for suppression of the inflammatory resp...

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Detalles Bibliográficos
Autores principales: Turco, Michelle Marian, Sousa, Marcelo Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131895/
https://www.ncbi.nlm.nih.gov/pubmed/25040221
http://dx.doi.org/10.1021/bi500593e