Mechanistic Insights into the Allosteric Modulation of Opioid Receptors by Sodium Ions

[Image: see text] The idea of sodium ions altering G-protein-coupled receptor (GPCR) ligand binding and signaling was first suggested for opioid receptors (ORs) in the 1970s and subsequently extended to other GPCRs. Recently published ultra-high-resolution crystal structures of GPCRs, including that...

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Detalles Bibliográficos
Autores principales: Shang, Yi, LeRouzic, Valerie, Schneider, Sebastian, Bisignano, Paola, Pasternak, Gavril W., Filizola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131901/
https://www.ncbi.nlm.nih.gov/pubmed/25073009
http://dx.doi.org/10.1021/bi5006915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131901/
https://www.ncbi.nlm.nih.gov/pubmed/25073009
http://dx.doi.org/10.1021/bi5006915

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