Functional Balance between the Hemagglutinin and Neuraminidase of Influenza A(H1N1)pdm09 HA D222 Variants

D222G/N substitutions in A(H1N1)pdm09 hemagglutinin may be associated with increased binding of viruses causing low respiratory tract infections and human pathogenesis. We assessed the impact of such substitutions on the balance between hemagglutinin binding and neuraminidase cleavage, viral growth...

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Detalles Bibliográficos
Autores principales: Casalegno, Jean-Sébastien, Ferraris, Olivier, Escuret, Vanessa, Bouscambert, Maude, Bergeron, Corinne, Linès, Laetitia, Excoffier, Thierry, Valette, Martine, Frobert, Emilie, Pillet, Sylvie, Pozzetto, Bruno, Lina, Bruno, Ottmann, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131921/
https://www.ncbi.nlm.nih.gov/pubmed/25119465
http://dx.doi.org/10.1371/journal.pone.0104009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131921/
https://www.ncbi.nlm.nih.gov/pubmed/25119465
http://dx.doi.org/10.1371/journal.pone.0104009

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