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Divergent Effects of Liraglutide, Exendin-4, and Sitagliptin on Beta-Cell Mass and Indicators of Pancreatitis in a Mouse Model of Hyperglycaemia

AIMS: Glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP4) inhibitors improve glucose tolerance by still incompletely understood mechanisms. Each class of antihyperglycemic drugs has also been proposed to increase pancreatitis risk. Here, we compare systematically the...

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Detalles Bibliográficos
Autores principales: Mondragon, Angeles, Davidsson, Daniel, Kyriakoudi, Styliana, Bertling, Annika, Gomes-Faria, Rosa, Cohen, Patrizia, Rothery, Stephen, Chabosseau, Pauline, Rutter, Guy A., da Silva Xavier, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132080/
https://www.ncbi.nlm.nih.gov/pubmed/25119717
http://dx.doi.org/10.1371/journal.pone.0104873