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1α,25-Dihydroxyvitamin D(3) Ameliorates Seawater Aspiration-Induced Acute Lung Injury via NF-κB and RhoA/Rho Kinase Pathways

INTRODUCTION: Inflammation and pulmonary edema are involved in the pathogenesis of seawater aspiration-induced acute lung injury (ALI). Although several studies have reported that 1α,25-Dihydroxyvitamin D(3) (calcitriol) suppresses inflammation, it has not been confirmed to be effective in seawater...

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Detalles Bibliográficos
Autores principales: Zhang, Minlong, Dong, Mingqing, Liu, Wei, Wang, Li, Luo, Ying, Li, Zhichao, Jin, Faguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132109/
https://www.ncbi.nlm.nih.gov/pubmed/25118599
http://dx.doi.org/10.1371/journal.pone.0104507