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Essential Domains of Schizosaccharomyces pombe Rad8 Required for DNA Damage Response
Schizosaccharomyces pombe Rad8 is a conserved protein homologous to S. cerevisiae Rad5 and human HLTF that is required for error-free postreplication repair by contributing to polyubiquitylation of PCNA. It has three conserved domains: an E3 ubiquitin ligase motif, a SNF2-family helicase domain, and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132169/ https://www.ncbi.nlm.nih.gov/pubmed/24875629 http://dx.doi.org/10.1534/g3.114.011346 |