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Essential Domains of Schizosaccharomyces pombe Rad8 Required for DNA Damage Response

Schizosaccharomyces pombe Rad8 is a conserved protein homologous to S. cerevisiae Rad5 and human HLTF that is required for error-free postreplication repair by contributing to polyubiquitylation of PCNA. It has three conserved domains: an E3 ubiquitin ligase motif, a SNF2-family helicase domain, and...

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Detalles Bibliográficos
Autores principales:	Ding, Lin, Forsburg, Susan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2014
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132169/ https://www.ncbi.nlm.nih.gov/pubmed/24875629 http://dx.doi.org/10.1534/g3.114.011346

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