Linking Genetics to Structural Biology: Complex Heterozygosity Screening with Actin Alanine Scan Alleles Identifies Functionally Related Surfaces on Yeast Actin

Previous genome-level genetic interaction screens with the single essential actin gene of yeast identified 238 nonessential genes that upon deletion result in deleterious, digenic complex haploinsufficiences with an actin null allele. Deletion alleles of these 238 genes were tested for complex heter...

Descripción completa

Detalles Bibliográficos
Autores principales: DiPrima, Stephanie, Haarer, Brian, Viggiano, Susan, Pons, Carles, Myers, Chad L., Amberg, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132179/
https://www.ncbi.nlm.nih.gov/pubmed/24938290
http://dx.doi.org/10.1534/g3.114.012054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132179/
https://www.ncbi.nlm.nih.gov/pubmed/24938290
http://dx.doi.org/10.1534/g3.114.012054

Ejemplares similares