Cargando…

Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile

BACKGROUND: The cross talk between the stroma and cancer cells plays a major role in phenotypic modulation. During peritoneal carcinomatosis ovarian cancer cells interact with mesenchymal stem cells (MSC) resulting in increased metastatic ability. Understanding the transcriptomic changes underlying...

Descripción completa

Detalles Bibliográficos
Autores principales: Lis, Raphael, Touboul, Cyril, Halabi, Najeeb M, Madduri, Abishek Sainath, Querleu, Denis, Mezey, Jason, Malek, Joel A, Suhre, Karsten, Rafii, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132214/
https://www.ncbi.nlm.nih.gov/pubmed/24597747
http://dx.doi.org/10.1186/1479-5876-12-59