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Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile
BACKGROUND: The cross talk between the stroma and cancer cells plays a major role in phenotypic modulation. During peritoneal carcinomatosis ovarian cancer cells interact with mesenchymal stem cells (MSC) resulting in increased metastatic ability. Understanding the transcriptomic changes underlying...
Autores principales: | Lis, Raphael, Touboul, Cyril, Halabi, Najeeb M, Madduri, Abishek Sainath, Querleu, Denis, Mezey, Jason, Malek, Joel A, Suhre, Karsten, Rafii, Arash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132214/ https://www.ncbi.nlm.nih.gov/pubmed/24597747 http://dx.doi.org/10.1186/1479-5876-12-59 |
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