Down-regulation of Sp1 suppresses cell proliferation, clonogenicity and the expressions of stem cell markers in nasopharyngeal carcinoma

BACKGROUND: Transcription factor Sp1 is multifaceted, with the ability to function as an oncogene or a tumor suppressor, depending on the cellular context. We previously reported that Sp1 is required for the transcriptional activation of the key oncogenes in nasopharyngeal carcinoma (NPC), including...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-Ping, Zhang, Hua, Wang, Hong-Bo, Li, Yan-Xian, Liu, Gui-Hong, Xing, Shan, Li, Man-Zhi, Zeng, Mu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132216/
https://www.ncbi.nlm.nih.gov/pubmed/25099028
http://dx.doi.org/10.1186/s12967-014-0222-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132216/
https://www.ncbi.nlm.nih.gov/pubmed/25099028
http://dx.doi.org/10.1186/s12967-014-0222-1

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