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The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection

BACKGROUND: Host genetic factors are thought to modulated the severity of disease caused by infection with the 2009 H1N1 pandemic influenza virus (H1N1pdm09). The human CCR5 gene encodes a cytokine receptor important for cell-mediated immune response against H1N1pdm09. A 32-bp polymorphic deletion i...

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Detalles Bibliográficos
Autores principales: Sironi, Manuela, Cagliani, Rachele, Pontremoli, Chiara, Rossi, Marianna, Migliorino, Guglielmo, Clerici, Mario, Gori, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132245/
https://www.ncbi.nlm.nih.gov/pubmed/25100510
http://dx.doi.org/10.1186/1756-0500-7-504